3,4-Dichlorobenzeneboronic acid → 5-(3,4-dichlorophenyl)-N-(2-hydroxycyclohexyl)-6-(pyridin-2-ylmethoxy)-2-(trifluoromethyl)pyridine-3-carboxamide
Reaction equation
[Br:1][c:2]1[c:3]([O:22][CH2:23][c:24]2[n:25][cH:26][cH:27][cH:28][cH:29]2)[n:4][c:5]([C:18]([F:19])([F:20])[F:21])[c:6]([C:7](=[O:8])[NH:9][CH:10]2[CH:11]([OH:16])[CH2:12][CH2:13][CH2:14][CH2:15]2)[cH:17]1.[Cl:30][c:31]1[cH:32][c:33]([B:38]([OH:39])[OH:40])[cH:34][cH:35][c:36]1[Cl:37]>>[c:2]1(-[c:33]2[cH:32][c:31]([Cl:30])[c:36]([Cl:37])[cH:35][cH:34]2)[c:3]([O:22][CH2:23][c:24]2[n:25][cH:26][cH:27][cH:28][cH:29]2)[n:4][c:5]([C:18]([F:19])([F:20])[F:21])[c:6]([C:7](=[O:8])[NH:9][CH:10]2[CH:11]([OH:16])[CH2:12][CH2:13][CH2:14][CH2:15]2)[cH:17]1Participants
3
Sources & evidence
- ORD record
- ord-abaa942757434c6eaf1e118ad5330f19
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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