Methanol → [5-(2-Chloropyrimidin-4-yl)-2-methoxyphenyl]methanol

HRID 1557519Notes

Reaction equation

HRID 1557519 reaction equation
[BH4-:18].[CH3:20][OH:21].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([O:16][CH3:17])[c:12]([CH:13]=[O:14])[cH:15]2)[n:7]1.[Na+:19]>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([O:16][CH3:17])[c:12]([CH2:13][OH:14])[cH:15]2)[n:7]1

Participants

5

Reactant 4

HCID 887MethanolHCID 923Sodium ionHCID 28123BorohydrideHCID 533635965-(2-Chloro-pyrimidin-4-yl)-2-methoxy-benzaldehyde

Product 1

HCID 53363597[5-(2-Chloropyrimidin-4-yl)-2-methoxyphenyl]methanol

Sources & evidence

ORD record
ord-f4750e352d334b62a4b06f0acbac4227
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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