3-Amino-4-fluorophenol → 2-(4-bromobenzyl)-N-(2-fluoro-5-hydroxyphenyl)-3-oxobutyramide

HRID 1557813Notes

Reaction equation

HRID 1557813 reaction equation
[C:1]([S:2][C:6]([CH:7]([C:8]([CH3:9])=[O:10])[CH2:11][c:12]1[cH:13][cH:14][c:15]([Br:18])[cH:16][cH:17]1)=[O:19])([CH3:3])([CH3:4])[CH3:5].[NH2:20][c:21]1[cH:22][c:23]([OH:28])[cH:24][cH:25][c:26]1[F:27]>>[C:6]([CH:7]([C:8]([CH3:9])=[O:10])[CH2:11][c:12]1[cH:13][cH:14][c:15]([Br:18])[cH:16][cH:17]1)(=[O:19])[NH:20][c:21]1[cH:22][c:23]([OH:28])[cH:24][cH:25][c:26]1[F:27]

Participants

3

Reactant 2

HCID 135191803-Amino-4-fluorophenolHCID 866423782-(4-bromobenzyl)-3-oxothiobutyric acid S-tert-butyl ester

Product 1

HCID 866423802-(4-bromobenzyl)-N-(2-fluoro-5-hydroxyphenyl)-3-oxobutyramide

Sources & evidence

ORD record
ord-e693b1b4c8aa458e8cdc495edc0f573b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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