Dimethyl Sulfoxide → 8-bromo-7-(2-chloro-6-fluorobenzyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
Reaction equation
[Br:1][c:2]1[n:3][c:4]2[n:5]([CH3:14])[c:6](=[O:13])[n:7]([CH3:8])[c:9](=[O:12])[c:10]2[nH:11]1.[C:15](=[O:16])([O-:17])[O-:18].[CH3:33][S:34]([CH3:35])=[O:36].[CH3:37][CH2:38][OH:39].[Cl:21][c:22]1[c:23]([CH2:24][Br:25])[c:26]([F:30])[cH:27][cH:28][cH:29]1.[K+:19].[K+:20].[K:31].[OH2:32]>>[Br:1][c:2]1[n:3][c:4]2[n:5]([CH3:14])[c:6](=[O:13])[n:7]([CH3:8])[c:9](=[O:12])[c:10]2[n:11]1[CH2:24][c:23]1[c:22]([Cl:21])[cH:29][cH:28][cH:27][c:26]1[F:30]Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-6b4226f80ce44ea09b43c9f0f9fb0a81
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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