Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 155944Generated: November 2, 2026

Dimethylformamide → racemic (2'R,3R,4'S)-6-chloro-4'-(3-chlorophenyl)-2,3-dihydro-1'-methyl-2'-(2-methylphenyl)-2,6'-dioxo spiro[indole-3,3'-piperidine]-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/155944

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantMethyl iodideHCID 6328—
ReactantEthyl AcetateHCID 8857—
ReactantLithium ionHCID 28486—
ReactantHydrideHCID 166653—
Reactantracemic (2'R,3R,4'S)-6-chloro-4'-(3-chlorophenyl)-2,3-dihydro-2'-(2-methylphenyl)-2,6'-dioxospiro[indole-3,3'-piperidine]-1-carboxylic acid tert-butyl esterHCID 90866629—
Productracemic (2'R,3R,4'S)-6-chloro-4'-(3-chlorophenyl)-2,3-dihydro-1'-methyl-2'-(2-methylphenyl)-2,6'-dioxo spiro[indole-3,3'-piperidine]-1-carboxylic acid tert-butyl esterHCID 90718123—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-9de9328c0f3540e986646b17d80e4657
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)