Tert-butyl 2-methylaziridine-1-carboxylate → N-tert-butoxycarbonyl 1-(5-fluorobenzofur-7-yl)-2-aminopropane

HRID 1559672Notes

Reaction equation

HRID 1559672 reaction equation
[C:12]([CH3:13])([CH3:14])([CH3:15])[O:16][C:17](=[O:18])[N:19]1[CH:20]([CH3:22])[CH2:21]1.[F:1][c:2]1[cH:3][c:4]([Br:11])[c:5]2[c:6]([cH:7][cH:8][o:9]2)[cH:10]1>>[F:1][c:2]1[cH:3][c:4]([CH2:21][CH:20]([NH:19][C:17]([O:16][C:12]([CH3:13])([CH3:14])[CH3:15])=[O:18])[CH3:22])[c:5]2[c:6]([cH:7][cH:8][o:9]2)[cH:10]1

Participants

3

Reactant 2

HCID 10942718Tert-butyl 2-methylaziridine-1-carboxylateHCID 221448167-Bromo-5-fluoro-1-benzofuran

Product 1

HCID 22144858N-tert-butoxycarbonyl 1-(5-fluorobenzofur-7-yl)-2-aminopropane

Sources & evidence

ORD record
ord-68359694ec5e48aab6d80423d731d919
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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