(4,4-Difluoropiperidin-1-yl)[5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]methanone → 6-Bromo-5-(1-isopropyl-piperidin-4-yloxy)-1H-indole-2-carboxylic acid ethyl ester
Reaction equation
[CH2:30]([CH3:31])[O:32][C:33](=[O:34])[c:35]1[nH:36][c:37]2[cH:38][c:39]([Br:45])[c:40]([OH:44])[cH:41][c:42]2[cH:43]1.[F:1][C:2]1([F:3])[CH2:4][CH2:5][N:6]([C:7]([c:8]2[nH:9][c:10]3[c:11]([cH:12]2)[cH:13][c:14]([O:15][CH:20]2[CH2:21][CH2:22][N:23]([CH:26]([CH3:27])[CH3:28])[CH2:24][CH2:25]2)[cH:16][cH:17]3)=[O:18])[CH2:19][CH2:29]1>>[CH:20]1([O:44][c:40]2[c:39]([Br:45])[cH:38][c:37]3[nH:36][c:35]([C:33]([O:32][CH2:30][CH3:31])=[O:34])[cH:43][c:42]3[cH:41]2)[CH2:21][CH2:22][N:23]([CH:26]([CH3:27])[CH3:28])[CH2:24][CH2:25]1Participants
3
Sources & evidence
- ORD record
- ord-f1309dbde66a4f91bb0c9039d90c86b5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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