Toluene → 5-Morpholin-4-yl-1-(2-trimethylsilanylethoxymethyl)-1H-pyrrolo[2,3-b]pyridine
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[n:8]([CH2:11][O:12][CH2:13][CH2:14][Si:15]([CH3:16])([CH3:17])[CH3:18])[cH:9][cH:10]2.[CH2:19]1[CH2:20][O:21][CH2:22][CH2:23][NH:24]1.[CH3:25][c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1.[O:34]=[C:35]([CH:36]=[CH:37][c:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1)[CH:44]=[CH:45][c:46]1[cH:47][cH:48][cH:49][cH:50][cH:51]1.[O:52]=[C:53]([CH:54]=[CH:55][c:56]1[cH:57][cH:58][cH:59][cH:60][cH:61]1)[CH:62]=[CH:63][c:64]1[cH:65][cH:66][cH:67][cH:68][cH:69]1.[O:70]=[C:71]([CH:72]=[CH:73][c:74]1[cH:75][cH:76][cH:77][cH:78][cH:79]1)[CH:80]=[CH:81][c:82]1[cH:83][cH:84][cH:85][cH:86][cH:87]1.[Pd:32].[Pd:33]>>[c:2]1([N:24]2[CH2:19][CH2:20][O:21][CH2:22][CH2:23]2)[cH:3][c:4]2[c:5]([n:6][cH:7]1)[n:8]([CH2:11][O:12][CH2:13][CH2:14][Si:15]([CH3:16])([CH3:17])[CH3:18])[cH:9][cH:10]2Participants
6
Sources & evidence
- ORD record
- ord-ec2e97e392c44b43bd5af0ff835c35d5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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