2-Bromo-5-(2-(trimethylsilyl)ethynyl)pyridine → (3aRS,6aSR)-1-Methyl-3-(5-trimethylsilanylethynyl-pyridin-2-yl)-hexahydro-cyclopenta-imidazol-2-one

HRID 1560351Notes

Reaction equation

HRID 1560351 reaction equation
[Br:1][c:2]1[n:3][cH:4][c:5]([C:8]#[C:9][Si:10]([CH3:11])([CH3:12])[CH3:13])[cH:6][cH:7]1.[CH3:14][N:15]1[C:16](=[O:23])[NH:17][CH:18]2[CH:19]1[CH2:20][CH2:21][CH2:22]2>>[c:2]1([N:17]2[C:16](=[O:23])[N:15]([CH3:14])[CH:19]3[CH:18]2[CH2:22][CH2:21][CH2:20]3)[n:3][cH:4][c:5]([C:8]#[C:9][Si:10]([CH3:11])([CH3:12])[CH3:13])[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 129830922-Bromo-5-(2-(trimethylsilyl)ethynyl)pyridineHCID 59655249(3aRS,6aSR)-1-Methyl-hexahydro-cyclopentaimidazol-2-one

Product 1

HCID 67436711(3aRS,6aSR)-1-Methyl-3-(5-trimethylsilanylethynyl-pyridin-2-yl)-hexahydro-cyclopenta-imidazol-2-one

Sources & evidence

ORD record
ord-45584ab293124964bb67c94ac8ac202a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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