Methanol → Tert-butyl 4-(3-sulfamoylpropyl)piperazine-1-carboxylate

HRID 1560520Notes

Reaction equation

HRID 1560520 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([CH2:14][CH2:15][CH2:16][S:17]([NH:18][CH:19]([c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)(=[O:32])=[O:33])[CH2:12][CH2:13]1.[CH3:34][OH:35].[OH-:36].[OH-:38].[Pd+2:37]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([CH2:14][CH2:15][CH2:16][S:17]([NH2:18])(=[O:32])=[O:33])[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 672053494-[3-(Benzhydryl-sulfamoyl)-propyl]-piperazine-1-carboxylic acid tert-butyl ester

Product 1

HCID 67205279Tert-butyl 4-(3-sulfamoylpropyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-2b01fe0bb56e453e9cc59c5cb15d9594
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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