1-(2,5-Dichlorobenzyl)-7-iodo-3,4-dihydro-1H-pyrido[2,3-b]pyrazine → {4-[1-(2,5-Dichlorobenzyl)-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl]phenyl}-(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone

HRID 1561622Notes

Reaction equation

HRID 1561622 reaction equation
[Cl:1][c:2]1[c:3]([CH2:4][N:5]2[c:6]3[c:7]([n:11][cH:12][c:13]([I:15])[cH:14]3)[NH:8][CH2:9][CH2:10]2)[cH:16][c:17]([Cl:20])[cH:18][cH:19]1.[N:21]1([CH:26]2[CH2:27][CH2:28][N:29]([C:32](=[O:33])[c:34]3[cH:35][cH:36][c:37]([B:40]4[O:41][C:42]([CH3:43])([CH3:44])[C:45]([CH3:46])([CH3:47])[O:48]4)[cH:38][cH:39]3)[CH2:30][CH2:31]2)[CH2:22][CH2:23][CH2:24][CH2:25]1>>[Cl:1][c:2]1[c:3]([CH2:4][N:5]2[c:6]3[c:7]([n:11][cH:12][c:13](-[c:37]4[cH:36][cH:35][c:34]([C:32]([N:29]5[CH2:28][CH2:27][CH:26]([N:21]6[CH2:22][CH2:23][CH2:24][CH2:25]6)[CH2:31][CH2:30]5)=[O:33])[cH:39][cH:38]4)[cH:14]3)[NH:8][CH2:9][CH2:10]2)[cH:16][c:17]([Cl:20])[cH:18][cH:19]1

Participants

3

Reactant 2

HCID 578860791-(2,5-Dichlorobenzyl)-7-iodo-3,4-dihydro-1H-pyrido[2,3-b]pyrazineHCID 57886103[4-(Pyrrolidin-1-yl)piperidin-1-yl][4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanone

Product 1

HCID 57885830{4-[1-(2,5-Dichlorobenzyl)-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl]phenyl}-(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone

Sources & evidence

ORD record
ord-bfe8bf57429946d7ae168ef35b67a11e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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