Morpholin-2-ylmethanol → 2-[2-(Hydroxymethyl)morpholin-4-yl]-5-[[1-[[4-hydroxy-2-(trifluoromethyl)phenyl]methyl]indazol-5-yl]methylidene]-1,3-thiazol-4-one

HRID 1561696Notes

Reaction equation

HRID 1561696 reaction equation
[CH2:1]([S:2][C:4]1=[N:8][C:7](=[O:9])[C:6](=[CH:10][c:11]2[cH:12][c:13]3[cH:14][n:15][n:16]([CH2:20][c:21]4[c:22]([C:28]([F:29])([F:30])[F:31])[cH:23][c:24]([OH:27])[cH:25][cH:26]4)[c:17]3[cH:18][cH:19]2)[S:5]1)[CH3:3].[O:32]1[CH:33]([CH2:38][OH:39])[CH2:34][NH:35][CH2:36][CH2:37]1>>[C:4]1([N:35]2[CH2:34][CH:33]([CH2:38][OH:39])[O:32][CH2:37][CH2:36]2)=[N:8][C:7](=[O:9])[C:6](=[CH:10][c:11]2[cH:12][c:13]3[cH:14][n:15][n:16]([CH2:20][c:21]4[c:22]([C:28]([F:29])([F:30])[F:31])[cH:23][c:24]([OH:27])[cH:25][cH:26]4)[c:17]3[cH:18][cH:19]2)[S:5]1

Participants

3

Reactant 2

HCID 3497988Morpholin-2-ylmethanolHCID 672415782-Ethylsulfanyl-5-[1-(4-hydroxy-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-thiazol-4-one

Product 1

HCID 767562902-[2-(Hydroxymethyl)morpholin-4-yl]-5-[[1-[[4-hydroxy-2-(trifluoromethyl)phenyl]methyl]indazol-5-yl]methylidene]-1,3-thiazol-4-one

Sources & evidence

ORD record
ord-ac043d317f8745e8ae472267530013b2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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