Methanol → 8-Bromo-7-isopropoxy-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Reaction equation
[CH3:26][OH:27].[F:1][C:2]([F:3])([F:4])[C:22]([N:5]1[CH2:6][CH2:7][c:8]2[c:9]([cH:13][c:14]([Br:21])[c:15]([O:17][CH:18]([CH3:19])[CH3:20])[cH:16]2)[CH:10]([CH3:12])[CH2:11]1)=[O:23].[Na+:25].[OH-:24].[OH2:28]>>[NH:5]1[CH2:6][CH2:7][c:8]2[c:9]([cH:13][c:14]([Br:21])[c:15]([O:17][CH:18]([CH3:19])[CH3:20])[cH:16]2)[CH:10]([CH3:12])[CH2:11]1Participants
6
Sources & evidence
- ORD record
- ord-56a0a856141e4bf6910d1eb4d4f0dfd8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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