2-Aminopyrimidine-5-boronic acid, pinacol ester → HCID 53378053, compound

HRID 1561822Notes

Reaction equation

HRID 1561822 reaction equation
[CH3:1][C:2]1([CH3:3])[C:4]([CH3:5])([CH3:6])[O:7][B:8]([c:9]2[cH:10][n:11][c:12]([NH2:15])[n:13][cH:14]2)[O:16]1.[Cl:17][c:18]1[n:19][c:20]([N:39]2[CH2:40][CH2:41][O:42][CH2:43][CH2:44]2)[c:21]2[c:22]([n:23]1)[cH:24][cH:25][c:26]([CH2:28][N:29]1[CH2:30][CH2:31][CH:32]([C:35]([CH3:36])([CH3:37])[OH:38])[CH2:33][CH2:34]1)[n:27]2>>[c:9]1(-[c:18]2[n:19][c:20]([N:39]3[CH2:40][CH2:41][O:42][CH2:43][CH2:44]3)[c:21]3[c:22]([n:23]2)[cH:24][cH:25][c:26]([CH2:28][N:29]2[CH2:30][CH2:31][CH:32]([C:35]([CH3:36])([CH3:37])[OH:38])[CH2:33][CH2:34]2)[n:27]3)[cH:10][n:11][c:12]([NH2:15])[n:13][cH:14]1

Participants

3

Reactant 2

HCID 177502122-Aminopyrimidine-5-boronic acid, pinacol esterHCID 584049702-(1-((2-Chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)piperidin-4-yl)propan-2-ol

Product 1

HCID 53378053HCID 53378053, compound

Sources & evidence

ORD record
ord-33e903d9df204efd82d8cd4edd51185b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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