4-Bromo-3-fluorotoluene → 2-(2-Fluoro-4-methylphenyl)-5-(1-phenylvinyl)thiazolo[5,4-b]pyridine

HRID 1562292Notes

Reaction equation

HRID 1562292 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH3:6])[cH:7][c:8]1[F:9].[Cl:10][c:11]1[c:12]([N:13]=[C:14]=[S:15])[cH:16][cH:17][c:18]([Cl:19])[n:20]1.[O:21]1[CH:22]([c:27]2[cH:28][c:29]([F:50])[c:30](-[c:33]3[s:34][c:35]4[n:36][c:37]([C:42](=[CH2:43])[c:44]5[cH:45][cH:46][cH:47][cH:48][cH:49]5)[cH:38][cH:39][c:40]4[n:41]3)[cH:31][cH:32]2)[O:26][CH2:25][CH2:24][CH2:23]1>>[CH3:22][c:27]1[cH:28][c:29]([F:50])[c:30](-[c:33]2[s:34][c:35]3[n:36][c:37]([C:42](=[CH2:43])[c:44]4[cH:45][cH:46][cH:47][cH:48][cH:49]4)[cH:38][cH:39][c:40]3[n:41]2)[cH:31][cH:32]1

Participants

4

Reactant 3

HCID 5732804-Bromo-3-fluorotolueneHCID 671118192-(4-(1,3-Dioxan-2-yl)-2-fluorophenyl)-5-(1-phenylvinyl)thiazolo[5,4-b]pyridineHCID 715192602,6-Dichloro-3-isothiocyanatopyridine

Product 1

HCID 591748892-(2-Fluoro-4-methylphenyl)-5-(1-phenylvinyl)thiazolo[5,4-b]pyridine

Sources & evidence

ORD record
ord-0a0b164a409d4097a36b8d38424db378
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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