Acetonitrile → 7-(3-Aminomethyl-4-methyl-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

HRID 1562426노트

반응식

HRID 1562426 반응식
[CH3:29][C:30]#[N:31].[Cl:1][c:2]1[c:3]([F:20])[c:4]([F:19])[cH:5][c:6]2[c:7](=[O:18])[c:8]([C:15](=[O:16])[OH:17])[cH:9][n:10]([CH:12]3[CH2:13][CH2:14]3)[c:11]12.[NH2:21][CH2:22][CH:23]1[CH2:24][NH:25][CH2:26][CH:27]1[CH3:28]>>[Cl:1][c:2]1[c:3]([N:25]2[CH2:24][CH:23]([CH2:22][NH2:21])[CH:27]([CH3:28])[CH2:26]2)[c:4]([F:19])[cH:5][c:6]2[c:7](=[O:18])[c:8]([C:15](=[O:16])[OH:17])[cH:9][n:10]([CH:12]3[CH2:13][CH2:14]3)[c:11]12

참가 물질

4

반응물 3

HCID 6342AcetonitrileHCID 4583498(4-Methylpyrrolidin-3-yl)methanamineHCID 98359418-Chloro-1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

생성물 1

HCID 139330897-(3-Aminomethyl-4-methyl-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

출처 및 근거

ORD 기록
ord-fe9a1d612c334decb6b307a375ec6928
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

반응 노트

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