Water → Ethyl 5-[2,5-difluoro-4-(2-methoxy-3,5-dimethyl-4-pyridinyl)phenyl]-1-(oxolan-3-yl)pyrazole-4-carboxylate
Reaction equation
[C:44](=[O:45])([O-:46])[O-:47].[CH2:50]1[O:51][CH2:52][CH2:53][O:54][CH2:55]1.[Cs+:48].[Cs+:49].[F:1][c:2]1[c:3](-[c:18]2[c:19]([C:28](=[O:29])[O:30][CH2:31][CH3:32])[cH:20][n:21][n:22]2[CH:23]2[CH2:24][O:25][CH2:26][CH2:27]2)[cH:4][c:5]([F:17])[c:6]([B:8]2[O:9][C:10]([CH3:11])([CH3:12])[C:13]([CH3:14])([CH3:15])[O:16]2)[cH:7]1.[I:33][c:34]1[c:35]([CH3:43])[c:36]([O:41][CH3:42])[n:37][cH:38][c:39]1[CH3:40].[OH2:133].[cH:56]1[cH:57][cH:58][c:59]([P:60]([Pd:61]([P:62]([c:63]2[cH:64][cH:65][cH:66][cH:67][cH:68]2)([c:69]2[cH:70][cH:71][cH:72][cH:73][cH:74]2)[c:75]2[cH:76][cH:77][cH:78][cH:79][cH:80]2)([P:81]([c:82]2[cH:83][cH:84][cH:85][cH:86][cH:87]2)([c:88]2[cH:89][cH:90][cH:91][cH:92][cH:93]2)[c:94]2[cH:95][cH:96][cH:97][cH:98][cH:99]2)[P:100]([c:101]2[cH:102][cH:103][cH:104][cH:105][cH:106]2)([c:107]2[cH:108][cH:109][cH:110][cH:111][cH:112]2)[c:113]2[cH:114][cH:115][cH:116][cH:117][cH:118]2)([c:119]2[cH:120][cH:121][cH:122][cH:123][cH:124]2)[c:125]2[cH:126][cH:127][cH:128][cH:129][cH:130]2)[cH:131][cH:132]1>>[F:1][c:2]1[c:3](-[c:18]2[c:19]([C:28](=[O:29])[O:30][CH2:31][CH3:32])[cH:20][n:21][n:22]2[CH:23]2[CH2:24][O:25][CH2:26][CH2:27]2)[cH:4][c:5]([F:17])[c:6](-[c:34]2[c:35]([CH3:43])[c:36]([O:41][CH3:42])[n:37][cH:38][c:39]2[CH3:40])[cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-97015ffbd0864c92af5033b7773773e3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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