3,5-Dimethyl-4-hydroxybenzonitrile → 4-{2-[2-(4-Chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclopentyl-ethoxy}-3,5-dimethyl-benzonitrile
Reaction equation
[CH3:27][c:28]1[cH:29][c:30]([C:31]#[N:32])[cH:33][c:34]([CH3:37])[c:35]1[OH:36].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[c:11]([n:12]2[CH:13]([CH2:14][OH:15])[CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20]2)[cH:21][c:22]([F:26])[c:23]([F:25])[cH:24]3)[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[c:11]([n:12]2[CH:13]([CH2:14][O:15][c:35]2[c:28]([CH3:27])[cH:29][c:30]([C:31]#[N:32])[cH:33][c:34]2[CH3:37])[CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20]2)[cH:21][c:22]([F:26])[c:23]([F:25])[cH:24]3)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-35dc2c25299b4e08a3191fbb0de5f1d1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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