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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 156304Generated: October 26, 2026

Tetrahydrofuran → Methyl 5-(4-chlorophenyl)-6-(2,4-dichlorophenyl)-2-(3,4-difluorophenyl)-3-oxo-2,3-dihydrofuro[2,3-b]pyridine-2-carboxylate

https://huagongshe.com/reaction/156304

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
Reactant(Trimethylsilyl)amideHCID 53627528—
ReactantMethyl {[5-(4-chlorophenyl)-3-cyano-6-(2,4-dichlorophenyl)pyridin-2-yl]oxy}(3,4-difluorophenyl)acetateHCID 86602010—
ProductMethyl 5-(4-chlorophenyl)-6-(2,4-dichlorophenyl)-2-(3,4-difluorophenyl)-3-oxo-2,3-dihydrofuro[2,3-b]pyridine-2-carboxylateHCID 21984819—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-bdce492f8b2a4ae0843a0cbc2280624e
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)