Acetic Acid → 6-fluoro-9-{[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-3,4,9,10-tetrahydro-2H-pyrano[2,3-h]isoquinolin-1(8H)-one
Reaction equation
[C:36]([BH3-:37])#[N:38].[CH3:32][C:33](=[O:34])[OH:35].[CH3:40][OH:41].[F:18][c:19]1[cH:20][c:21]2[c:22]([CH2:28][CH2:29][CH:30]=[O:31])[cH:23][nH:24][c:25]2[cH:26][cH:27]1.[NH2:1][CH:2]1[CH2:3][c:4]2[c:5]([c:6]([F:15])[cH:7][c:8]3[c:13]2[C:12](=[O:14])[NH:11][CH2:10][CH2:9]3)[O:16][CH2:17]1.[Na+:39]>>[NH:1]([CH:2]1[CH2:3][c:4]2[c:5]([c:6]([F:15])[cH:7][c:8]3[c:13]2[C:12](=[O:14])[NH:11][CH2:10][CH2:9]3)[O:16][CH2:17]1)[CH2:30][CH2:29][CH2:28][c:22]1[c:21]2[cH:20][c:19]([F:18])[cH:27][cH:26][c:25]2[nH:24][cH:23]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-4a0fc2405c284104a6d07bd2f68b3e94
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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