Diethyl Ether → 2-(2-Fluoro-5-piperazin-1-yl-phenyl)-1-methyl-1H-benzoimidazole

HRID 1563212Notes

Reaction equation

HRID 1563212 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][c:16](-[c:21]3[n:22][c:23]4[c:24]([n:25]3[CH3:26])[cH:27][cH:28][cH:29][cH:30]4)[c:17]([F:20])[cH:18][cH:19]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH3:34][CH2:35][O:36][CH2:37][CH3:38].[Cl:31][CH2:32][Cl:33]>>[NH:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][c:16](-[c:21]3[n:22][c:23]4[c:24]([n:25]3[CH3:26])[cH:27][cH:28][cH:29][cH:30]4)[c:17]([F:20])[cH:18][cH:19]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 3283Diethyl EtherHCID 6344DichloromethaneHCID 686709934-[4-Fluoro-3-(1-methyl-1H-benzoimidazol-2-yl)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester

Product 1

HCID 595680772-(2-Fluoro-5-piperazin-1-yl-phenyl)-1-methyl-1H-benzoimidazole

Sources & evidence

ORD record
ord-c1d9dc9eb8a24beab0801d40b7ee9df5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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