Methanol → 3,5-Dimethyl-3-ethyl-4-hydroxypiperidine

HRID 1563710Notes

Reaction equation

HRID 1563710 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][C:10]([CH2:16][CH3:17])([CH3:18])[CH:11]([OH:15])[CH:12]([CH3:14])[CH2:13]1.[CH3:19][OH:20].[H:21][H:22].[OH-:23].[OH-:25].[Pd+2:24]>>[NH:8]1[CH2:9][C:10]([CH2:16][CH3:17])([CH3:18])[CH:11]([OH:15])[CH:12]([CH3:14])[CH2:13]1

Participants

6

Reactant 5

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 230036911-Benzyl-3,5-dimethyl-3-ethyl-4-hydroxypiperidineHCID 178418361HCID 178418361, compound

Product 1

HCID 230036803,5-Dimethyl-3-ethyl-4-hydroxypiperidine

Sources & evidence

ORD record
ord-b113834a73fd44538831324a6b5e4d84
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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