Benzo[b]thiophene-3-boronic acid pinacol ester → (5-Benzo[b]thiophen-3-yl-[1,2,4]triazolo[1,5-a]pyrazin-8-yl)-(4-morpholin-4-ylphenyl)amine

HRID 1563967Notes

Reaction equation

HRID 1563967 reaction equation
[Br:1][c:2]1[cH:3][n:4][c:5]([NH:11][c:12]2[cH:13][cH:14][c:15]([N:18]3[CH2:19][CH2:20][O:21][CH2:22][CH2:23]3)[cH:16][cH:17]2)[c:6]2[n:7]1[n:8][cH:9][n:10]2.[CH3:24][C:25]1([CH3:26])[C:27]([CH3:28])([CH3:29])[O:30][B:31]([c:32]2[c:33]3[c:34]([s:35][cH:36]2)[cH:37][cH:38][cH:39][cH:40]3)[O:41]1>>[c:2]1(-[c:32]2[c:33]3[c:34]([s:35][cH:36]2)[cH:37][cH:38][cH:39][cH:40]3)[cH:3][n:4][c:5]([NH:11][c:12]2[cH:13][cH:14][c:15]([N:18]3[CH2:19][CH2:20][O:21][CH2:22][CH2:23]3)[cH:16][cH:17]2)[c:6]2[n:7]1[n:8][cH:9][n:10]2

Participants

3

Reactant 2

HCID 10658979Benzo[b]thiophene-3-boronic acid pinacol esterHCID 57589931(5-Bromo-[1,2,4]triazolo[1,5-a]pyrazin-8-yl)-(4-morpholin-4-ylphenyl)amine

Product 1

HCID 24888779(5-Benzo[b]thiophen-3-yl-[1,2,4]triazolo[1,5-a]pyrazin-8-yl)-(4-morpholin-4-ylphenyl)amine

Sources & evidence

ORD record
ord-a340acd697134cb0b5bfe8415bc25ef0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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