HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1564228Generated: November 4, 2026
Hydrochloric Acid → 3-Cyano-1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(4-hydroxypiperazin-1-yl)-4-oxoquinoline
https://huagongshe.com/reaction/1564228
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Dimethyl Sulfoxide | HCID 679 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Piperazin-1-ol | HCID 12463393 | — |
| Reactant | 1-Cyclopropyl-3-cyano-1,4-dihydro-4-oxo-6,7,8-trifluoroquinoline | HCID 14302347 | — |
| Product | 3-Cyano-1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(4-hydroxypiperazin-1-yl)-4-oxoquinoline | HCID 20189430 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (1/10) |
|---|
| ORD ID | ord-8a6e97cd7b544af698171449d1d6ae1c |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (1/10) |
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