5-Ethynylpyrimidin-2-amine → 5-[5-(4-Chloro-phenyl)-7-methyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-pyrimidin-2-ylamine

HRID 1564234Notes

Reaction equation

HRID 1564234 reaction equation
[C:19](#[CH:20])[c:21]1[cH:22][n:23][c:24]([NH2:27])[n:25][cH:26]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([CH3:14])[cH:13]2)[n:15][cH:16][c:17]3[I:18])[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([CH3:14])[cH:13]2)[n:15][cH:16][c:17]3[C:20]#[C:19][c:21]2[cH:22][n:23][c:24]([NH2:27])[n:25][cH:26]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 161090215-Ethynylpyrimidin-2-amineHCID 670013225-(4-Chloro-phenyl)-3-iodo-7-methyl-pyrazolo[1,5-a]pyrimidine

Product 1

HCID 670007795-[5-(4-Chloro-phenyl)-7-methyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-pyrimidin-2-ylamine

Sources & evidence

ORD record
ord-83c16095cb7945d98c2d1adf728fcc17
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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