Ethanol → 3-(1-Ethyl-5-fluoro-indan-1-yl)-1H-indol-7-ylamine

HRID 1564258Notes

Reaction equation

HRID 1564258 reaction equation
[CH2:1]([O:2][C:3](=[O:4])[NH:10][c:11]1[cH:12][cH:13][cH:14][c:15]2[c:16]([C:20]3([CH2:30][CH3:31])[CH2:21][CH2:22][c:23]4[cH:24][c:25]([F:29])[cH:26][cH:27][c:28]43)[cH:17][nH:18][c:19]12)[c:5]1[cH:6][cH:7][cH:8][cH:9][cH:32]1.[CH3:33][CH2:34][OH:35].[OH-:36].[OH-:38].[Pd+2:37]>>[NH2:10][c:11]1[cH:12][cH:13][cH:14][c:15]2[c:16]([C:20]3([CH2:30][CH3:31])[CH2:21][CH2:22][c:23]4[cH:24][c:25]([F:29])[cH:26][cH:27][c:28]43)[cH:17][nH:18][c:19]12

Participants

5

Reactant 4

HCID 702EthanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 58941681[3-(1-Ethyl-5-fluoro-indan-1-yl)-1H-indol-7-yl]-carbamic acid benzyl ester

Product 1

HCID 589417073-(1-Ethyl-5-fluoro-indan-1-yl)-1H-indol-7-ylamine

Sources & evidence

ORD record
ord-74b78be705f14ca48cf03d6c79fb9fb0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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