6-[[3-[(8-Hydroxyoctyl)carbamoyl]phenyl]sulfonyl]-4-[(3-methoxyphenyl)amino]-8-methylquinoline-3-carboxamide → tert-butyl [5-[1-[tert-butyl(dimethyl)silyl]oxy-2-[6-[2-[4-[[3-[3-carbamoyl-4-(3-methoxyanilino)-8-methylquinolin-6-yl]sulfonylbenzoyl]amino]phenyl]ethoxy]hexyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]ethyl]-2-oxo-1H-quinolin-8-yl] carbonate
Reaction equation
[NH2:45][c:46]1[cH:47][cH:48][c:49]([CH2:50][CH2:51][O:52][CH2:53][CH2:54][CH2:55][CH2:56][CH2:57][CH2:58][N:59]([C:60]([O:61][C:62]([CH3:63])([CH3:64])[CH3:65])=[O:66])[CH2:67][CH:68]([O:69][Si:70]([CH3:71])([CH3:72])[C:73]([CH3:74])([CH3:75])[CH3:76])[c:77]2[c:78]3[cH:79][cH:80][c:81](=[O:95])[nH:82][c:83]3[c:84]([O:87][C:88](=[O:89])[O:90][C:91]([CH3:92])([CH3:93])[CH3:94])[cH:85][cH:86]2)[cH:96][cH:97]1.[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][NH:10][C:11](=[O:12])[c:13]1[cH:14][c:15]([S:19](=[O:20])(=[O:21])[c:22]2[cH:23][c:24]3[c:25]([NH:36][c:37]4[cH:38][c:39]([O:43][CH3:44])[cH:40][cH:41][cH:42]4)[c:26]([C:33](=[O:34])[NH2:35])[cH:27][n:28][c:29]3[c:30]([CH3:32])[cH:31]2)[cH:16][cH:17][cH:18]1>>[C:11](=[O:12])([c:13]1[cH:14][c:15]([S:19](=[O:20])(=[O:21])[c:22]2[cH:23][c:24]3[c:25]([NH:36][c:37]4[cH:38][c:39]([O:43][CH3:44])[cH:40][cH:41][cH:42]4)[c:26]([C:33](=[O:34])[NH2:35])[cH:27][n:28][c:29]3[c:30]([CH3:32])[cH:31]2)[cH:16][cH:17][cH:18]1)[NH:45][c:46]1[cH:47][cH:48][c:49]([CH2:50][CH2:51][O:52][CH2:53][CH2:54][CH2:55][CH2:56][CH2:57][CH2:58][N:59]([C:60]([O:61][C:62]([CH3:63])([CH3:64])[CH3:65])=[O:66])[CH2:67][CH:68]([O:69][Si:70]([CH3:71])([CH3:72])[C:73]([CH3:74])([CH3:75])[CH3:76])[c:77]2[c:78]3[cH:79][cH:80][c:81](=[O:95])[nH:82][c:83]3[c:84]([O:87][C:88](=[O:89])[O:90][C:91]([CH3:92])([CH3:93])[CH3:94])[cH:85][cH:86]2)[cH:96][cH:97]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-e052ea6470df44908c2e9db7125c0905
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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