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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1564541Generated: October 31, 2026

Water → 5-{6-[2-(2,4-Dichloro-phenyl)-ethylamino]-2-methoxy-pyrimidin-4-yl}-thiophene-2-carboxylic acid

https://huagongshe.com/reaction/1564541

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
Reactant1,2-DimethoxyethaneHCID 8071—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladiumHCID 23938—
ReactantFluoride IonHCID 28179—
ReactantCesium cationHCID 104967—
Reactant6-Chloro-N-[2-(2,4-dichlorophenyl)ethyl]-2-methoxy-4-pyrimidinamineHCID 57636004—
Reactant5-(5,5-Dimethyl-[1,3,2]dioxaborinan-2-yl)-thiophene-2-carboxylic acidHCID 68932577—
Product5-{6-[2-(2,4-Dichloro-phenyl)-ethylamino]-2-methoxy-pyrimidin-4-yl}-thiophene-2-carboxylic acidHCID 57635999—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-122d2ef2284d4e838381c7a0ccc6fb22
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)