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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1564548Generated: October 31, 2026

Dimethylformamide → 6-{(3SR,4RS)-3-(3,4-Dichloro-phenyl)-4-[(3-fluoro-4-trifluoromethyl-benzyl)-methyl-amino]-pyrrolidin-1-yl}-6-oxo-hexanenitrile

https://huagongshe.com/reaction/1564548

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
Reactant5-Bromo-1-{(3SR,4RS)-3-(3,4-dichloro-phenyl)-4-[(3-fluoro-4-trifluoromethyl-benzyl)-methyl-amino]-pyrrolidin-1-yl}-pentan-1-oneHCID 72253475—
ReactantHCID 178511842HCID 178511842—
Product6-{(3SR,4RS)-3-(3,4-Dichloro-phenyl)-4-[(3-fluoro-4-trifluoromethyl-benzyl)-methyl-amino]-pyrrolidin-1-yl}-6-oxo-hexanenitrileHCID 75148866—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-d10963674ab9447e820feb31366819c6
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)