Pyridine → 2-Bromo-4-(bromomethyl)-5-methyl-1,3-thiazole

HRID 1564610Notes

Reaction equation

HRID 1564610 reaction equation
[Br:5][c:6]1[s:7][c:8]([CH3:13])[c:9]([CH2:11][OH:12])[n:10]1.[Cl:20][CH2:21][Cl:22].[S:1]([Br:2])([Br:3])=[O:4].[cH:14]1[cH:15][cH:16][n:17][cH:18][cH:19]1>>[Br:3][CH2:11][c:9]1[c:8]([CH3:13])[s:7][c:6]([Br:5])[n:10]1

Participants

5

Reactant 4

HCID 1049PyridineHCID 6344DichloromethaneHCID 68176Thionyl bromideHCID 58127549(2-Bromo-5-methylthiazol-4-yl)methanol

Product 1

HCID 671901442-Bromo-4-(bromomethyl)-5-methyl-1,3-thiazole

Sources & evidence

ORD record
ord-21b268f17e2d4c7398ff718775ba9688
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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