4-Amino-2-chloro-6-methylphenol → N2-(3-chloro-4-hydroxy-5-methylphenyl)-5-fluoro-N4-(3-hydroxyphenyl)-2,4-pyrimidinediamine

HRID 1564799Notes

Reaction equation

HRID 1564799 reaction equation
[Cl:17][c:18]1[cH:19][c:20]([NH2:21])[cH:22][c:23]([CH3:26])[c:24]1[OH:25].[Cl:1][c:2]1[n:3][cH:4][c:5]([F:16])[c:6]([NH:8][c:9]2[cH:10][c:11]([OH:15])[cH:12][cH:13][cH:14]2)[n:7]1>>[c:2]1([NH:21][c:20]2[cH:19][c:18]([Cl:17])[c:24]([OH:25])[c:23]([CH3:26])[cH:22]2)[n:3][cH:4][c:5]([F:16])[c:6]([NH:8][c:9]2[cH:10][c:11]([OH:15])[cH:12][cH:13][cH:14]2)[n:7]1

Participants

3

Reactant 2

HCID 27744394-Amino-2-chloro-6-methylphenolHCID 220604512-chloro-5-fluoro-N-(3-hydroxyphenyl)-4-pyrimidineamine

Product 1

HCID 22060815N2-(3-chloro-4-hydroxy-5-methylphenyl)-5-fluoro-N4-(3-hydroxyphenyl)-2,4-pyrimidinediamine

Sources & evidence

ORD record
ord-fc7c5635418c42aa86adae6b677d0868
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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