Acetate → Methyl 4-(3-methyl-6-{[6-(1-methyl-1H-pyrazol-4-yl)-4-oxospiro[chroman-2,4'-piperidin]-1'-yl]carbonyl}-1H-indazol-1-yl)benzoate

HRID 1564857Notes

Reaction equation

HRID 1564857 reaction equation
[C:57]([O-:58])(=[O:59])[CH3:60].[C:62]([O-:63])(=[O:64])[CH3:65].[CH3:41][O:42][C:43](=[O:44])[c:45]1[cH:46][cH:47][c:48]([B:51]([OH:52])[OH:53])[cH:49][cH:50]1.[CH3:7][c:8]1[n:9][nH:10][c:11]2[cH:12][c:13]([C:17](=[O:18])[N:19]3[CH2:20][CH2:21][C:22]4([O:23][c:24]5[cH:25][cH:26][c:27](-[c:33]6[cH:34][n:35][n:36]([CH3:38])[cH:37]6)[cH:28][c:29]5[C:30](=[O:32])[CH2:31]4)[CH2:39][CH2:40]3)[cH:14][cH:15][c:16]12.[Cl:54][CH2:55][Cl:56].[Cu+2:61].[cH:1]1[cH:2][cH:3][n:4][cH:5][cH:6]1>>[CH3:7][c:8]1[n:9][n:10](-[c:48]2[cH:47][cH:46][c:45]([C:43]([O:42][CH3:41])=[O:44])[cH:50][cH:49]2)[c:11]2[cH:12][c:13]([C:17](=[O:18])[N:19]3[CH2:20][CH2:21][C:22]4([O:23][c:24]5[cH:25][cH:26][c:27](-[c:33]6[cH:34][n:35][n:36]([CH3:38])[cH:37]6)[cH:28][c:29]5[C:30](=[O:32])[CH2:31]4)[CH2:39][CH2:40]3)[cH:14][cH:15][c:16]12

Participants

7

Reactant 6

HCID 175Acetate2×HCID 1049PyridineHCID 6344DichloromethaneHCID 27099Cupric cationHCID 27343694-Methoxycarbonylphenylboronic acidHCID 178434311HCID 178434311, compound

Product 1

HCID 58208718Methyl 4-(3-methyl-6-{[6-(1-methyl-1H-pyrazol-4-yl)-4-oxospiro[chroman-2,4'-piperidin]-1'-yl]carbonyl}-1H-indazol-1-yl)benzoate

Sources & evidence

ORD record
ord-2049855356b94557ba7b47ba6474e545
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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