Formic Acid → tert-Butyl 4-(piperazin-1-yl)piperidine-1-carboxylate

HRID 1564978Notes

Reaction equation

HRID 1564978 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([N:14]2[CH2:15][CH2:16][N:17]([C:20]([O:21][CH2:22][c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)=[O:29])[CH2:18][CH2:19]2)[CH2:12][CH2:13]1.[CH3:33][OH:34].[CH:30]([OH:31])=[O:32]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([N:14]2[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 284Formic AcidHCID 887MethanolHCID 18971584Benzyl 4-(1-(tert-butoxycarbonyl)piperidin-4-yl)piperazine-1-carboxylate

Product 1

HCID 17750358tert-Butyl 4-(piperazin-1-yl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-68898118a936496bbad08db895ee3b95
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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