3-(1,3-Oxazol-5-yl)aniline → 5-fluoro-N4-(3-hydroxyphenyl)-N2-(3-(1,3-oxazol-5-yl)phenyl]-2,4-pyrimidinediamine

HRID 1565267Notes

Reaction equation

HRID 1565267 reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([F:16])[c:6]([NH:8][c:9]2[cH:10][c:11]([OH:15])[cH:12][cH:13][cH:14]2)[n:7]1.[o:17]1[cH:18][n:19][cH:20][c:21]1-[c:22]1[cH:23][c:24]([NH2:25])[cH:26][cH:27][cH:28]1>>[c:2]1([NH:25][c:24]2[cH:23][c:22](-[c:21]3[o:17][cH:18][n:19][cH:20]3)[cH:28][cH:27][cH:26]2)[n:3][cH:4][c:5]([F:16])[c:6]([NH:8][c:9]2[cH:10][c:11]([OH:15])[cH:12][cH:13][cH:14]2)[n:7]1

Participants

3

Reactant 2

HCID 27392893-(1,3-Oxazol-5-yl)anilineHCID 220604512-chloro-5-fluoro-N-(3-hydroxyphenyl)-4-pyrimidineamine

Product 1

HCID 220606035-fluoro-N4-(3-hydroxyphenyl)-N2-(3-(1,3-oxazol-5-yl)phenyl]-2,4-pyrimidinediamine

Sources & evidence

ORD record
ord-54ff67c30f4845ebb78c975bc2b7a4ab
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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