1-Cyclopropyl-5-methyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid → 1-Cyclopropyl-6,8-difluoro-5-methyl-1,4-dihydro-7-(3'-aminomethyl-4'-hydroxy-piperidin-1-yl)-4-oxo-quinoline-3-carboxylic acid
Reaction equation
[CH:1]1([n:4]2[cH:5][c:6]([C:19](=[O:20])[OH:21])[c:7](=[O:18])[c:8]3[c:9]([CH3:17])[c:10]([F:16])[c:11]([F:15])[c:12]([F:14])[c:13]23)[CH2:2][CH2:3]1.[NH2:22][CH2:23][CH:24]1[CH2:25][NH:26][CH2:27][CH2:28][CH:29]1[OH:30]>>[CH:1]1([n:4]2[cH:5][c:6]([C:19](=[O:20])[OH:21])[c:7](=[O:18])[c:8]3[c:9]([CH3:17])[c:10]([F:16])[c:11]([N:26]4[CH2:25][CH:24]([CH2:23][NH2:22])[CH:29]([OH:30])[CH2:28][CH2:27]4)[c:12]([F:14])[c:13]23)[CH2:2][CH2:3]1Participants
3
Sources & evidence
- ORD record
- ord-b17734c215ee4f92869d6a0f7d2b489a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…