2-Amino-4-methyl-thiazole-5-sulfonic acid (2-hydroxy-1-hydroxymethyl-1-methyl-ethyl)-amide → 7-Trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid [5-(2-hydroxy-1-hydroxymethyl-1-methyl-ethylsulfamoyl)-4-methyl-thiazol-2-yl]-amide
Reaction equation
[F:1][C:2]([c:3]1[cH:4][c:5](-[c:15]2[cH:16][cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]2)[n:6][c:7]2[n:8]1[n:9][cH:10][c:11]2[C:12](=[O:13])[OH:14])([F:25])[F:26].[OH:27][CH2:28][C:29]([CH3:30])([CH2:31][OH:32])[NH:33][S:34](=[O:35])(=[O:36])[c:37]1[c:38]([CH3:43])[n:39][c:40]([NH2:42])[s:41]1>>[F:1][C:2]([c:3]1[cH:4][c:5](-[c:15]2[cH:16][cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]2)[n:6][c:7]2[n:8]1[n:9][cH:10][c:11]2[C:12](=[O:13])[NH:42][c:40]1[n:39][c:38]([CH3:43])[c:37]([S:34]([NH:33][C:29]([CH2:28][OH:27])([CH3:30])[CH2:31][OH:32])(=[O:35])=[O:36])[s:41]1)([F:25])[F:26]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-5f5fb1ce441f45ff88f5374800eae0cd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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