Bromide ion → Tert-butyl 4-[tert-butyl(dimethyl)silyl]oxy-2-[(3,4-dichlorophenyl)-hydroxymethyl]-2-propylpyrrolidine-1-carboxylate
Reaction equation
[Br-:1].[C:11]([CH3:12])([CH3:13])([CH3:14])[O:15][C:16](=[O:17])[N:18]1[C:19]([CH2:31][CH2:32][CH3:33])([CH:34]=[O:35])[CH2:20][CH:21]([O:23][Si:24]([CH3:25])([CH3:26])[C:27]([CH3:28])([CH3:29])[CH3:30])[CH2:22]1.[Cl:2][c:3]1[cH:4][c:5]([Mg+:10])[cH:6][cH:7][c:8]1[Cl:9]>>[Cl:2][c:3]1[cH:4][c:5]([CH:34]([C:19]2([CH2:31][CH2:32][CH3:33])[N:18]([C:16]([O:15][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:17])[CH2:22][CH:21]([O:23][Si:24]([CH3:25])([CH3:26])[C:27]([CH3:28])([CH3:29])[CH3:30])[CH2:20]2)[OH:35])[cH:6][cH:7][c:8]1[Cl:9]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-3f9b9a89fa6148b0b6e568f90323ce53
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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