Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1566376Generated: November 4, 2026

Tetrahydrofuran → 5-[6-(hydroxymethyl)-3H-imidazo[4,5-c]pyridin-3-yl]-3-{1-[2-(trifluoromethyl)phenyl]ethoxy}thiophene-2-carboxamide

https://huagongshe.com/reaction/1566376

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTetrabutylammoniumHCID 16028—
ReactantFluoride IonHCID 28179—
Reactant5-[6-({[tert-butyl(dimethyl)silyl]oxy}methyl)-3H-imidazo[4,5-c]pyridin-3-yl]-3-{1-[2-(trifluoromethyl)phenyl]ethoxy}thiophene-2-carboxamideHCID 68768728—
Product5-[6-(hydroxymethyl)-3H-imidazo[4,5-c]pyridin-3-yl]-3-{1-[2-(trifluoromethyl)phenyl]ethoxy}thiophene-2-carboxamideHCID 68767275—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-f0fe2bb9a6f54249949e6445f8479efd
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)