Methanol → 4-Fluoro-1-{4-[2-(2-hydroxy-phenyl)-7-methyl-quinazolin-4-yl]-piperazin-1-yl}-4-methyl-pentan-1-one
Reaction equation
[CH3:35][OH:36].[F:1][C:2]([CH:3]=[CH:4][C:5](=[O:6])[N:7]1[CH2:8][CH2:9][N:10]([c:13]2[n:14][c:15](-[c:24]3[c:25]([OH:30])[cH:26][cH:27][cH:28][cH:29]3)[n:16][c:17]3[cH:18][c:19]([CH3:23])[cH:20][cH:21][c:22]23)[CH2:11][CH2:12]1)([CH3:31])[CH3:32].[H:33][H:34]>>[F:1][C:2]([CH2:3][CH2:4][C:5](=[O:6])[N:7]1[CH2:8][CH2:9][N:10]([c:13]2[n:14][c:15](-[c:24]3[c:25]([OH:30])[cH:26][cH:27][cH:28][cH:29]3)[n:16][c:17]3[cH:18][c:19]([CH3:23])[cH:20][cH:21][c:22]23)[CH2:11][CH2:12]1)([CH3:31])[CH3:32]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-b5210b7e5a71486c9f657365a6a76f75
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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