Acetone → 8-chloro-7-p-tolyl-2-((6-(trifluoromethyl)pyridin-3-yl)methyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
Reaction equation
[CH3:37][C:38](=[O:39])[CH3:40].[Cl:19][CH2:20][c:21]1[cH:22][cH:23][c:24]([C:27]([F:28])([F:29])[F:30])[n:25][cH:26]1.[Cl:1][c:2]1[c:3]2[n:4]([cH:5][cH:6][c:7]1-[c:8]1[cH:9][cH:10][c:11]([CH3:14])[cH:12][cH:13]1)[c:15](=[O:18])[nH:16][n:17]2.[K+:31].[K+:32].[O-:33][C:34]([O-:35])=[O:36]>>[Cl:1][c:2]1[c:3]2[n:4]([cH:5][cH:6][c:7]1-[c:8]1[cH:9][cH:10][c:11]([CH3:14])[cH:12][cH:13]1)[c:15](=[O:18])[n:16]([CH2:20][c:21]1[cH:22][cH:23][c:24]([C:27]([F:28])([F:29])[F:30])[n:25][cH:26]1)[n:17]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-0ba035cdfa29430ea3565184e301f130
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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