4-Iodobenzonitrile → 4-[5-(4-Isopropyl-piperazine-1-carbonyl)-2-(morpholine-4-carbonyl)-indol-1-yl]-benzonitrile

HRID 1567188Notes

Reaction equation

HRID 1567188 reaction equation
[CH:1]([CH3:2])([CH3:3])[N:4]1[CH2:5][CH2:6][N:7]([C:10](=[O:11])[c:12]2[cH:13][c:14]3[cH:15][c:16]([C:21](=[O:22])[N:23]4[CH2:24][CH2:25][O:26][CH2:27][CH2:28]4)[nH:17][c:18]3[cH:19][cH:20]2)[CH2:8][CH2:9]1.[I:29][c:30]1[cH:31][cH:32][c:33]([C:34]#[N:35])[cH:36][cH:37]1>>[CH:1]([CH3:2])([CH3:3])[N:4]1[CH2:5][CH2:6][N:7]([C:10](=[O:11])[c:12]2[cH:13][c:14]3[cH:15][c:16]([C:21](=[O:22])[N:23]4[CH2:24][CH2:25][O:26][CH2:27][CH2:28]4)[n:17](-[c:30]4[cH:31][cH:32][c:33]([C:34]#[N:35])[cH:36][cH:37]4)[c:18]3[cH:19][cH:20]2)[CH2:8][CH2:9]1

Participants

3

Reactant 2

HCID 764674-IodobenzonitrileHCID 68683056[5-(4-Isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-morpholin-4-yl-methanone

Product 1

HCID 686807574-[5-(4-Isopropyl-piperazine-1-carbonyl)-2-(morpholine-4-carbonyl)-indol-1-yl]-benzonitrile

Sources & evidence

ORD record
ord-fd2c336af3dc484186be37fb8383c527
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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