Dichloromethane → 2-[4-(Chloromethyl)phenoxy][1,3]thiazolo[5,4-b]pyridine

HRID 156745Notes

Reaction equation

HRID 156745 reaction equation
[Cl:23][CH2:24][Cl:25].[S:19]([Cl:20])([Cl:21])=[O:22].[n:1]1[c:2]([O:10][c:11]2[cH:12][cH:13][c:14]([CH2:17][OH:18])[cH:15][cH:16]2)[s:3][c:4]2[n:5][cH:6][cH:7][cH:8][c:9]12>>[n:1]1[c:2]([O:10][c:11]2[cH:12][cH:13][c:14]([CH2:17][Cl:21])[cH:15][cH:16]2)[s:3][c:4]2[n:5][cH:6][cH:7][cH:8][c:9]12

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 24386Thionyl ChlorideHCID 57448386[4-([1,3]Thiazolo[5,4-b]pyridin-2-yloxy)phenyl]methanol

Product 1

HCID 574483872-[4-(Chloromethyl)phenoxy][1,3]thiazolo[5,4-b]pyridine

Sources & evidence

ORD record
ord-a144c07c0a8f404198abea2d50e0eb7d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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