Sodium ion → (5-Bromo-imidazo[1,2-a]pyrazin-8-yl)-[4-(4-pyridin-2-yl-[1,2,3]triazol-1-yl)-phenyl]amine

HRID 1567661Notes

Reaction equation

HRID 1567661 reaction equation
[Br:33][c:34]1[cH:35][n:36][c:37]([Br:43])[c:38]2[n:39]1[cH:40][cH:41][n:42]2.[CH3:124][c:125]1[cH:126][cH:127][cH:128][cH:129][cH:130]1.[CH3:62][C:63]([CH3:64])([O-:65])[CH3:66].[Na+:67].[O:106]=[C:107]([CH:108]=[CH:109][c:110]1[cH:111][cH:112][cH:113][cH:114][cH:115]1)[CH:116]=[CH:117][c:118]1[cH:119][cH:120][cH:121][cH:122][cH:123]1.[O:70]=[C:71]([CH:72]=[CH:73][c:74]1[cH:75][cH:76][cH:77][cH:78][cH:79]1)[CH:80]=[CH:81][c:82]1[cH:83][cH:84][cH:85][cH:86][cH:87]1.[O:88]=[C:89]([CH:90]=[CH:91][c:92]1[cH:93][cH:94][cH:95][cH:96][cH:97]1)[CH:98]=[CH:99][c:100]1[cH:101][cH:102][cH:103][cH:104][cH:105]1.[OH:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][NH:7][C:8](=[O:9])[c:10]2[cH:11][cH:12][c:13]([NH:14][c:15]3[c:16]4[n:17]([cH:18][cH:19][n:20]4)[c:21](-[c:22]4[cH:23][n:24][nH:25][cH:26]4)[cH:27][n:28]3)[cH:29][cH:30]2)[cH:31][cH:32]1.[Pd:68].[Pd:69].[n:44]1[c:45](-[c:50]2[n:51][n:52][n:53](-[c:55]3[cH:56][cH:57][c:58]([NH2:61])[cH:59][cH:60]3)[cH:54]2)[cH:46][cH:47][cH:48][cH:49]1>>[Br:33][c:34]1[cH:35][n:36][c:37]([NH:61][c:58]2[cH:57][cH:56][c:55](-[n:53]3[n:52][n:51][c:50](-[c:45]4[n:44][cH:49][cH:48][cH:47][cH:46]4)[cH:54]3)[cH:60][cH:59]2)[c:38]2[n:39]1[cH:40][cH:41][n:42]2

Participants

9

Reactant 8

HCID 923Sodium ionHCID 1140TolueneHCID 23938Palladium2×HCID 95417Dibenzylidene acetone3×HCID 45749132-Methylpropan-2-olateHCID 24857547N-(4-Hydroxybenzyl)-4-[5-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-ylamino]benzamideHCID 534859495,8-Dibromoimidazo[1,2-a]pyrazineHCID 590231334-(4-Pyridin-2-yl-[1,2,3]triazol-1-yl)-phenylamine

Product 1

HCID 59023107(5-Bromo-imidazo[1,2-a]pyrazin-8-yl)-[4-(4-pyridin-2-yl-[1,2,3]triazol-1-yl)-phenyl]amine

Sources & evidence

ORD record
ord-fc613f6b02a2463d819fba5292640cf2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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