4-Bromo-m-cresol → 4-[4-(4-Bromo-3-methyl-phenoxymethyl)-phenyl]-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[Br:1][c:2]1[c:3]([CH3:9])[cH:4][c:5]([OH:8])[cH:6][cH:7]1.[C:10]([CH3:11])([CH3:12])([CH3:13])[O:14][C:15](=[O:16])[N:17]1[CH2:18][CH2:19][CH:20]([c:23]2[cH:24][cH:25][c:26]([CH2:29][OH:30])[cH:27][cH:28]2)[CH2:21][CH2:22]1>>[Br:1][c:2]1[c:3]([CH3:9])[cH:4][c:5]([O:8][CH2:29][c:26]2[cH:25][cH:24][c:23]([CH:20]3[CH2:19][CH2:18][N:17]([C:15]([O:14][C:10]([CH3:11])([CH3:12])[CH3:13])=[O:16])[CH2:22][CH2:21]3)[cH:28][cH:27]2)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-f27ba16b81a14891841656d4b0a5ade8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…