1-Propanone, 3-amino-1-phenyl- → tert-butyl (3RS,4RS)-3-(naphthalen-2-ylmethoxy)-4-[4-(3-oxo-3-phenyl-propylcarbamoyl)-phenyl]-piperidine-1-carboxylate

HRID 1567977Notes

Reaction equation

HRID 1567977 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([O:23][CH2:24][c:25]2[cH:26][c:27]3[cH:28][cH:29][cH:30][cH:31][c:32]3[cH:33][cH:34]2)[CH:11]([c:14]2[cH:15][cH:16][c:17]([C:18](=[O:19])[OH:20])[cH:21][cH:22]2)[CH2:12][CH2:13]1.[NH2:35][CH2:36][CH2:37][C:38](=[O:39])[c:40]1[cH:41][cH:42][cH:43][cH:44][cH:45]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([O:23][CH2:24][c:25]2[cH:26][c:27]3[cH:28][cH:29][cH:30][cH:31][c:32]3[cH:33][cH:34]2)[CH:11]([c:14]2[cH:15][cH:16][c:17]([C:18](=[O:19])[NH:35][CH2:36][CH2:37][C:38](=[O:39])[c:40]3[cH:41][cH:42][cH:43][cH:44][cH:45]3)[cH:21][cH:22]2)[CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 4085651-Propanone, 3-amino-1-phenyl-HCID 22127190(3RS,4RS)-4-(1-tert-butoxycarbonyl-3-naphthalen-2-ylmethoxy-piperidin-4-yl)-benzoic acid

Product 1

HCID 54453433tert-butyl (3RS,4RS)-3-(naphthalen-2-ylmethoxy)-4-[4-(3-oxo-3-phenyl-propylcarbamoyl)-phenyl]-piperidine-1-carboxylate

Sources & evidence

ORD record
ord-87b2d0e0c32d402996a7e2f70ad2e239
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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