(2,4-Dimethoxypyrimidin-5-yl)boronic acid → 3-(2,4-Dimethoxy-pyrimidin-5-yl)-7-(2-pyrrolidin-1-yl-ethyl)-[1,5]naphthyridine

HRID 1568044Notes

Reaction equation

HRID 1568044 reaction equation
[Br:14][c:15]1[cH:16][n:17][c:18]2[cH:19][c:20]([CH2:25][CH2:26][N:27]3[CH2:28][CH2:29][CH2:30][CH2:31]3)[cH:21][n:22][c:23]2[cH:24]1.[CH3:1][O:2][c:3]1[n:4][cH:5][c:6]([B:11]([OH:12])[OH:13])[c:7]([O:9][CH3:10])[n:8]1>>[CH3:1][O:2][c:3]1[n:4][cH:5][c:6](-[c:15]2[cH:16][n:17][c:18]3[cH:19][c:20]([CH2:25][CH2:26][N:27]4[CH2:28][CH2:29][CH2:30][CH2:31]4)[cH:21][n:22][c:23]3[cH:24]2)[c:7]([O:9][CH3:10])[n:8]1

Participants

3

Reactant 2

HCID 2736209(2,4-Dimethoxypyrimidin-5-yl)boronic acidHCID 104028693-Bromo-7-(2-pyrrolidin-1-yl-ethyl)[1,5]naphthyridine

Product 1

HCID 104740223-(2,4-Dimethoxy-pyrimidin-5-yl)-7-(2-pyrrolidin-1-yl-ethyl)-[1,5]naphthyridine

Sources & evidence

ORD record
ord-cc6b09b94f044b2da58ee507e4c4e2e7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…