6-(4-Chloro-phenyl)-5-cyclopropylmethoxy-3-trifluoromethyl-pyrazine-2-carboxylic acid (2-cyclopropyl-2-hydroxy-propyl)-amide → (3-Chloro-phenyl)-5-cyclopropylmethoxy-3-trifluoromethyl-pyrazine-2-carboxylic acid (2-cyclopropyl-2-hydroxy-propyl)-amide
Reaction equation
[CH:1]1([C:4]([CH2:5][NH:6][C:7](=[O:8])[c:9]2[n:10][c:11](-[c:24]3[cH:25][cH:26][c:27]([Cl:28])[cH:29][cH:30]3)[c:12]([O:19][CH2:20][CH:21]3[CH2:22][CH2:23]3)[n:13][c:14]2[C:15]([F:16])([F:17])[F:18])([CH3:31])[OH:32])[CH2:2][CH2:3]1.[CH:33]1([C:34]([OH:35])([CH3:36])[CH2:37][NH:38][C:39]([c:40]2[c:41]([C:42]([F:43])([F:44])[F:45])[n:46][c:47]([Br:48])[c:49](-[c:52]3[cH:53][c:54]([Cl:58])[cH:55][cH:56][cH:57]3)[n:50]2)=[O:51])[CH2:59][CH2:60]1>>[CH:1]1([C:4]([CH2:5][NH:6][C:7](=[O:8])[c:9]2[n:10][c:11](-[c:52]3[cH:53][c:54]([Cl:58])[cH:55][cH:56][cH:57]3)[c:12]([O:19][CH2:20][CH:21]3[CH2:22][CH2:23]3)[n:13][c:14]2[C:15]([F:16])([F:17])[F:18])([CH3:31])[OH:32])[CH2:2][CH2:3]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-10e74e72d0e4416d96b52a121d0cc8c2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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