Potassium Cation → 4-(1-Methanesulfonyl-1,2,3,6-tetrahydro-pyridin-4-yl)-phenol

HRID 1568299Notes

Reaction equation

HRID 1568299 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8]2=[CH:13][CH2:12][N:11]([S:14](=[O:15])(=[O:16])[CH3:17])[CH2:10][CH2:9]2)[cH:6][cH:7]1.[C:20]([P:21]([C:22]([CH3:23])([CH3:24])[CH3:25])[c:26]1[cH:27][cH:28][cH:29][cH:30][c:31]1-[c:32]1[c:33]([CH:34]([CH3:35])[CH3:36])[cH:37][c:38]([CH:39]([CH3:40])[CH3:41])[cH:42][c:43]1[CH:44]([CH3:45])[CH3:46])([CH3:47])([CH3:48])[CH3:49].[CH3:106][CH2:107][O:108][CH2:109][CH3:110].[K+:19].[O:52]=[C:53]([CH:54]=[CH:55][c:56]1[cH:57][cH:58][cH:59][cH:60][cH:61]1)[CH:62]=[CH:63][c:64]1[cH:65][cH:66][cH:67][cH:68][cH:69]1.[O:70]=[C:71]([CH:72]=[CH:73][c:74]1[cH:75][cH:76][cH:77][cH:78][cH:79]1)[CH:80]=[CH:81][c:82]1[cH:83][cH:84][cH:85][cH:86][cH:87]1.[O:88]=[C:89]([CH:90]=[CH:91][c:92]1[cH:93][cH:94][cH:95][cH:96][cH:97]1)[CH:98]=[CH:99][c:100]1[cH:101][cH:102][cH:103][cH:104][cH:105]1.[OH-:18].[Pd:50].[Pd:51]>>[c:2]1([OH:18])[cH:3][cH:4][c:5]([C:8]2=[CH:13][CH2:12][N:11]([S:14](=[O:15])(=[O:16])[CH3:17])[CH2:10][CH2:9]2)[cH:6][cH:7]1

Participants

8

Reactant 7

HCID 813Potassium CationHCID 961HydroxideHCID 3283Diethyl EtherHCID 23938Palladium2×HCID 95417Dibenzylidene acetone3×HCID 11618717Di-tert-butyl(2',4',6'-tris(propan-2-yl)-(1,1'-biphenyl)-2-yl)phosphaneHCID 58111158HCID 58111158, compound

Product 1

HCID 579301164-(1-Methanesulfonyl-1,2,3,6-tetrahydro-pyridin-4-yl)-phenol

Sources & evidence

ORD record
ord-d5e4da07d8934f6587d250ea00faad6a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…