2-chloro-N,N-dimethylacetamide → 2-{7-[4-(4-Fluoro-phenyl)-1-methyl-butyl]-5-hydroxy-10,10-dimethyl-1,2,4,10-tetrahydro-9-oxa-3-aza-phenanthren-3-yl}-N,N-dimethyl-acetamide

HRID 1568495Notes

Reaction equation

HRID 1568495 reaction equation
[Cl:30][CH2:31][C:32](=[O:33])[N:34]([CH3:35])[CH3:36].[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][CH2:9][CH2:10][CH:11]([CH3:12])[c:13]2[cH:14][c:15]3[c:16]([c:17]([OH:19])[cH:18]2)[C:20]2=[C:25]([CH2:24][CH2:23][NH:22][CH2:21]2)[C:26]([CH3:28])([CH3:29])[O:27]3)[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][CH2:9][CH2:10][CH:11]([CH3:12])[c:13]2[cH:14][c:15]3[c:16]([c:17]([OH:19])[cH:18]2)[C:20]2=[C:25]([CH2:24][CH2:23][N:22]([CH2:31][C:32](=[O:33])[N:34]([CH3:35])[CH3:36])[CH2:21]2)[C:26]([CH3:28])([CH3:29])[O:27]3)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 758862-chloro-N,N-dimethylacetamideHCID 128007415,5-dimethyl-8-[5-(4-fluorophenyl)-2-pentyl]-10-hydroxy-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-d]pyridine

Product 1

HCID 213211412-{7-[4-(4-Fluoro-phenyl)-1-methyl-butyl]-5-hydroxy-10,10-dimethyl-1,2,4,10-tetrahydro-9-oxa-3-aza-phenanthren-3-yl}-N,N-dimethyl-acetamide

Sources & evidence

ORD record
ord-bdccd1e7275a492288b7a7e138879ba0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…