Methanol → 5,6,7,8-Tetrahydro-N-phenylpyrido[3,4-d]pyrimidin-4-amine

HRID 1568569Notes

Reaction equation

HRID 1568569 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][c:10]2[n:11][cH:12][n:13][c:14]([NH:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[c:15]2[CH2:16][CH2:17]1.[CH3:25][OH:26].[OH-:27].[OH-:29].[Pd+2:28]>>[NH:8]1[CH2:9][c:10]2[n:11][cH:12][n:13][c:14]([NH:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[c:15]2[CH2:16][CH2:17]1

Participants

5

Reactant 4

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 597717937-Benzyl-5,6,7,8-tetrahydro-N-phenylpyrido[3,4-d]pyrimidin-4-amine

Product 1

HCID 597717895,6,7,8-Tetrahydro-N-phenylpyrido[3,4-d]pyrimidin-4-amine

Sources & evidence

ORD record
ord-a5041e765eb54c6398d69cd980553c92
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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